Direct bilirubin blood test in Chiswick

What the test measures

Bilirubin is a yellow pigment made when old red blood cells are broken down. It travels to the liver, where it is changed into a water-soluble form called conjugated or direct bilirubin, which then passes into bile and out of the body. Direct bilirubin is the portion that has been through this liver processing step.

Measuring direct bilirubin is most useful when total bilirubin is raised. It helps separate a problem with the liver or the flow of bile from other causes, such as faster breakdown of red blood cells or Gilbert syndrome, a common and harmless inherited condition.

The price includes the blood sample taken at our Chiswick clinic, analysis at the Randox accredited laboratory, a practitioner review of your result with you, and a GP feedback report on request.

Who it is for

• A previous test showed raised total bilirubin and you want to understand it.
• You have noticed yellowing of the skin or eyes, dark urine or pale stools and your GP is aware.
• You have been told you may have Gilbert syndrome and want more detail.
• You are reviewing your liver health alongside other liver markers.

Understanding your result

Your report shows your direct bilirubin against the laboratory reference range. A raised direct bilirubin can point to the liver not clearing bilirubin properly, or to a blockage or narrowing in the bile ducts, for example from gallstones. A normal direct bilirubin with a raised total bilirubin often fits with Gilbert syndrome or increased red cell breakdown.

Bilirubin is always read with other liver tests such as ALT, ALP and GGT. A result outside the range is a prompt for discussion with your practitioner, not a diagnosis. New jaundice, especially with abdominal pain or fever, should be assessed by a GP or urgent care promptly.

Preparing for your test

Fasting is not usually required, although a short fast of around 8 hours can make results more consistent if you are being checked for Gilbert syndrome, as fasting itself raises bilirubin in that condition. We will confirm what is best for you when you book. Please tell us about any medicines and supplements you take, as some can affect liver tests.

For a broader liver picture, the Liver Function Check covers the core liver enzymes and total bilirubin, and Omnia Signature includes direct bilirubin among many other markers. You can also compare every blood test and price in Chiswick.

Questions

How much is a direct bilirubin test in Chiswick?

A direct bilirubin blood test at Omnia Lifestyle costs £39. The price includes your sample in Chiswick, analysis at an accredited laboratory, a practitioner review and a GP feedback report on request.

What is the difference between total and direct bilirubin?

Total bilirubin measures all bilirubin in the blood. Direct bilirubin is the part already processed by the liver. Comparing the two helps show where in the pathway a problem lies.

What is Gilbert syndrome?

It is a common inherited difference in how the liver processes bilirubin. Total bilirubin may be mildly raised, particularly when fasting or unwell, while direct bilirubin and other liver tests are usually normal. It is generally harmless.

Can this test diagnose liver disease?

No single marker can. Direct bilirubin is one piece of information that your practitioner reads with other liver tests, your symptoms and history before suggesting any next steps.