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A total protein blood test measures the combined amount of albumin and globulin proteins in your blood. It is booked as part of checking how the liver is working, as well as nutrition, hydration and immune health.
Total protein is the sum of two main groups of proteins in the blood. Albumin, made by the liver, keeps fluid inside blood vessels and carries hormones, medicines and nutrients. Globulins are a mixed group that includes antibodies made by the immune system, along with transport and clotting proteins.
Because the result reflects liver production, nutrition, hydration and immune activity together, total protein is a broad, general marker. It is most helpful when read alongside albumin, from which the globulin level can be worked out, and with other liver and kidney tests.
Your price includes the sample taken at our Chiswick clinic, analysis at the Randox accredited laboratory, a practitioner review of your result and a GP feedback report on request. No GP referral is needed.
A raised total protein can be caused by dehydration, which concentrates the blood, or by higher globulin levels, for example with long-term infection or inflammation. Occasionally a raised globulin needs further tests to look for an abnormal antibody pattern, which your practitioner can discuss. A low total protein can reflect reduced production by the liver, poor nutrition or absorption, or protein loss through the kidneys or gut.
Your report shows the laboratory reference range. A result outside it is a prompt for discussion with your practitioner, not a diagnosis.
No fasting is needed. Drink water normally, as being dehydrated can raise the result. Avoid very heavy exercise the day before. Tell us about the medicines you take, as some, including steroids and hormone treatments, can affect blood protein levels.
Total protein is included in Omnia Signature. For a focused look at the liver, the Liver Function Check covers albumin, bilirubin and the main liver enzymes. You can also view every blood test and price in Chiswick.
The total protein test costs £39. This includes your sample at our clinic, laboratory analysis, a practitioner review and a GP feedback report on request.
Not in the short term. Blood protein levels reflect what the liver and immune system make, so a high-protein diet does not usually change the result.
Albumin is the largest single protein in the blood. Total protein includes albumin plus globulins, and the difference between the two gives the globulin level.
Yes. When you are dehydrated the blood is more concentrated, which can make total protein appear higher than usual.