L-selectin blood test in Chiswick

What the test measures

L-selectin is an adhesion molecule found on the surface of most white blood cells, or leucocytes, which is where the L in its name comes from. It allows white cells to roll along and briefly grip the inner wall of blood vessels, an early step in leaving the bloodstream to reach lymph nodes or sites of inflammation. When white cells are activated, L-selectin is shed and a soluble form circulates in the blood.

Soluble L-selectin has been studied in relation to inflammation, immune activation and the health of the blood vessel lining. It is an emerging, specialist marker. It is not part of routine NHS testing and has limited use as a stand-alone screen, so it is best interpreted with established markers such as CRP, a full blood count and cholesterol.

The price includes the blood sample taken at our Chiswick clinic, analysis at the Randox accredited laboratory, a practitioner review of your result with you, and a GP feedback report on request.

Who it is for

• Your practitioner has suggested a specialist adhesion marker as part of a detailed review.
• You are already checking E-selectin or ICAM-1 and want the related marker.
• You have an inflammatory condition and are exploring immune and vessel markers.
• You want a baseline and understand the marker has limited routine use.

Understanding your result

Your report shows your L-selectin value and the laboratory reference range. Levels can shift with infection, inflammation and changes in white cell activity, and research has reported both higher and lower values in different conditions. This means a single result has no simple interpretation.

Your practitioner will consider your L-selectin value alongside your history, white cell count and other markers. A level outside the range is a prompt for discussion, not a diagnosis, and any decisions about your heart or immune health should be based on validated assessments with your GP.

Preparing for your test

No fasting is needed for L-selectin on its own. Please try to test when you have been well for at least two weeks without colds or infections, since these change white cell activity. Tell us about steroid or immune-modifying medicines you take. If you are adding cholesterol or glucose to the same appointment, we will advise on fasting when you book.

L-selectin is one of the blood vessel markers in Omnia Signature. A Full Blood Count gives an established view of your white cells. You can also see every blood test and price in Chiswick.

Questions

How much is an L-selectin test in Chiswick?

An L-selectin blood test at Omnia Lifestyle costs £109. This includes the sample at our Chiswick clinic, laboratory analysis, a practitioner review of your result and a GP feedback report on request.

How does L-selectin differ from E-selectin?

L-selectin is found on white blood cells, while E-selectin is produced by activated cells lining the blood vessels. Both help white cells attach to the vessel wall.

Is L-selectin a routine test?

No. It is a specialist marker used mainly in research and in-depth reviews. Most people start with established tests.

Can L-selectin diagnose a condition?

No. It adds detail but cannot diagnose or rule out any condition on its own. Your practitioner will explain how it fits with your other results.