Glutathione S-transferase Pi blood test in Chiswick

What the test measures

Glutathione S-transferases are a family of enzymes that attach glutathione to harmful compounds so the body can remove them. The Pi form is found in many tissues, including the brain, lungs, kidneys and red blood cells. When cells that contain it are damaged, GSTpi can be released into the bloodstream, which is why researchers have explored it as a possible sign of brain injury and stroke.

Research into GSTpi has also covered kidney injury and several cancers, but the marker is not used in routine NHS care and is not a screening test. Findings from studies have not yet produced clear guidance on how a single blood level should be acted on, so it is best used as a supporting marker alongside established tests and a clinical assessment.

The price includes your sample at our Chiswick clinic, analysis at the Randox accredited laboratory, a review of your result with an Omnia practitioner, and a GP feedback report on request.

Who it is for

• A specialist has requested GSTpi as part of an ongoing assessment.
• You are having a comprehensive health review that includes emerging markers and want each explained.
• You are following up a previous result with your practitioner.
• You understand that this marker gives context rather than a firm answer.

Understanding your result

Your report shows your GSTpi level with the laboratory reference range. Because this is a research marker, the range and its meaning are less settled than for routine tests. A raised level may reflect cell injury in one of several tissues, and red cell breakdown in the sample itself can also raise it, so it cannot identify a cause on its own.

Any value outside the range is a reason to talk it through, not a diagnosis. Your practitioner will explain what is and is not known and whether repeating the test or looking at standard markers would be more helpful. Anyone with sudden weakness, facial drooping, slurred speech or confusion should call 999 straight away rather than book a test.

Preparing for your test

No special preparation is usually needed, and fasting is not necessary. Keep taking your normal medicines. Let us know if you have had a recent illness, injury or surgery, as this may affect how the result is read, and we confirm any preparation when you book.

GSTpi is one of many markers in Omnia Signature, and if you want a check with a clearer clinical role, the Standard Screen covers blood count, liver, kidney and cholesterol. View every blood test and price in Chiswick.

Questions

How much is a Glutathione S-transferase Pi test in Chiswick?

The Glutathione S-transferase Pi test costs £129 at our Chiswick clinic. It includes the blood sample, analysis at the Randox accredited laboratory, a practitioner review, and a GP feedback report on request.

Is this the same as a glutathione test?

No. Glutathione is the antioxidant itself, while GSTpi is an enzyme that uses glutathione. They measure different things.

Can GSTpi detect a stroke or brain injury?

No. It has been studied in these areas, but stroke and brain injury are diagnosed through urgent clinical assessment and scans.

Should healthy people have this test?

It has limited value as a stand-alone screen. It is most suitable where a specialist or practitioner has a specific question.