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Measures CA 15-3 (cancer antigen 15-3), a protein mainly used by specialists to monitor known breast cancer during and after treatment. It is a tumour-associated marker and is always read alongside a clinical assessment.
CA 15-3 is a protein released from the surface of breast cells and some other tissues. Specialists mainly use it to track how a known breast cancer is responding to treatment, or to watch for changes over time in people who have already been treated. It is one of several tumour-associated markers and is interpreted as part of a wider plan of care.
CA 15-3 is not a screening test for breast cancer and cannot be used to check whether you have it. Many early breast cancers do not raise the level, while benign breast conditions, liver disease, lung conditions, pregnancy and some autoimmune conditions can raise it. Breast screening in the UK is carried out through mammograms in the NHS Breast Screening Programme. The price includes the blood sample taken at our Chiswick clinic, analysis at the Randox accredited laboratory, a review of your result with an Omnia practitioner and a GP feedback report on request.
Your report shows your CA 15-3 with the laboratory reference range. In monitoring, a steady trend over several results is usually more meaningful than a single value, and your specialist will compare results with imaging and your clinical progress. In someone without a breast cancer diagnosis, a raised level is most often due to another cause and needs medical review.
A normal level does not rule out breast cancer, so any breast lump, skin or nipple change should be seen by your GP. A figure outside the range simply flags something to discuss, rather than confirming a condition.
No fasting is required for this test. Let us know if you are pregnant or breastfeeding, and about any known liver or lung condition. Please stop biotin or high-dose hair, skin and nail supplements for 48 hours before your sample to avoid interference with the laboratory method.
CA 15-3 is included in Omnia Signature, our most comprehensive health check. Our hub sets out every blood test and price in Chiswick, or look up individual markers in the biomarker A to Z.
The CA 15-3 blood test costs £59. The price includes your sample at our Chiswick clinic, laboratory analysis, a practitioner review and a GP feedback report on request.
No. It is a tumour-associated marker used mainly to monitor known breast cancer. It cannot screen for or rule out breast cancer, and benign conditions can raise it.
That depends on your treatment plan, which is decided by your oncology team. If you are testing privately, it is helpful to share results with them.
See your GP promptly. A lump, change in shape, skin dimpling or nipple change needs a clinical examination, whatever a blood test shows.